AI and radiologists differ in the types and patient characteristics of false-positive findings in digital breast tomosynthesis breast cancer screening.
Key Details
- 1Study included 2,977 women (average age 58) and 3,183 DBT exams (2013–2017) from UCLA.
- 2AI-only false positives mostly flagged benign calcifications (40%), while radiologists mostly flagged masses (47%).
- 3AI and radiologists had nearly identical false-positive rates: 9.7% (AI) vs. 9.5% (radiologists).
- 4Of 541 false-positive exams, 43% were AI-only, 44% were radiologist-only, and 13% were flagged by both.
- 5AI-only false positives occurred in older women (average 60 years), less often with dense breasts (24%), and more often with prior surgical history (37%).
- 6Concordant (AI-radiologist) flagged findings needing biopsy were high-risk in 44% of cases.
Why It Matters
Identifying how AI and radiologists differ in false-positive findings can inform the design of AI tools to improve screening specificity and reduce unnecessary recalls, directly impacting efficiency and patient care in breast imaging.

Source
AuntMinnie
Related News

•Radiology Business
Meta Funds Ohio State’s Radiology AI Innovation Projects
Meta will fund Ohio State researchers to explore AI-driven advancements in radiology, including chest X-ray reporting and disease prediction.

•AuntMinnie
ChatGPT-5 Performs Poorly at Detecting Distal Radius Fractures on X-rays
ChatGPT-5 missed about half of distal radius fractures on x-rays, showing limited diagnostic capability in a real-world scenario.

•AuntMinnie
AI Triage Tool Speeds Up ICH Head CT Turnaround in ED
AI-based triage for intracranial hemorrhage on head CT reduced emergency department report turnaround by 13 minutes.