Back to all papers

DBENet: Dual-Branch Encoder Network for brain MRI lesion segmentation.

July 23, 2026pubmed logopapers

Authors

Zhao Q,Zhang Z,Cao T

Affiliations (3)

  • Department of Radiology, People's Hospital of Chongqing Liang Jiang New Area, Chongqing, China.
  • School of Computer Science, Qufu Normal University, Qufu, China.
  • Department of Radiology, Bishan District Traditional Chinese Medicine Hospital, Chongqing, China.

Abstract

Accurate brain lesion segmentation in Magnetic Resonance Imaging (MRI) remains challenging due to heterogeneous lesion appearance, variable scales, and ambiguous boundaries. We propose DBENet, a Dual-Branch Encoder Network for brain MRI lesion segmentation. The spatial and frequency branches first extract lesion-related features from complementary domains. The Spatial and Frequency Fusion (SFF) module then integrates these features into a hybrid lesion representation. In parallel, lesion-aware prompts are encoded by the Segment Anything Model (SAM) prompt encoder to generate prompt embeddings. Finally, the Multi-scale Attention Fusion (MAF) module takes the hybrid representation and prompt embeddings as inputs, and progressively integrates them across scales for contextual modeling and boundary refinement. Extensive experiments on the ISLES 2022 and BraTS 2018 datasets demonstrate that DBENet outperforms state-of-the-art approaches, achieving Dice scores of 0.8621 and 0.8261, respectively, while providing superior lesion localization and boundary delineation. Ablation studies confirm the complementary benefits of SFF and MAF. Furthermore, DBENet achieves a favorable balance between segmentation accuracy and computational cost, supporting practical implementation under moderate hardware constraints. Future work will extend DBENet to volumetric 3D segmentation. We will also investigate multimodal learning and foundation-model adaptation to improve robustness across diverse imaging protocols.

Topics

Journal Article

Ready to Sharpen Your Edge?

Subscribe to join 11k+ peers who rely on RadAI Slice. Get the essential weekly briefing that empowers you to navigate the future of radiology.

We respect your privacy. Unsubscribe at any time.