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HSMD: A Hilbert-scanning mamba dense network for 3D MRI reconstruction.

November 7, 2026pubmed logopapers

Authors

Liu Z,Chi J,Yang J,Liu B,Liu F

Affiliations (5)

  • College of Mechanical and Electrical Engineering, Qingdao University, Qingdao 266071, China.
  • College of Electronics and Information, Qingdao University, Qingdao 266071, China. Electronic address: [email protected].
  • College of Mechanical and Electrical Engineering, Qingdao University, Qingdao 266071, China. Electronic address: [email protected].
  • College of Electronics and Information, Qingdao University, Qingdao 266071, China.
  • School of Electrical Engineering and Computer Science, University of Queensland, Brisbane, QLD 4072, Australia.

Abstract

Long MRI acquisition times motivate the use of k-space undersampling for accelerated imaging, but undersampling often introduces aliasing artifacts and structural detail loss. Existing 2D slice-wise reconstruction methods fail to fully exploit inter-slice anatomical correlations. This study develops a Hilbert-Scanning Mamba Dense Network (HSMD) for high-quality 3D MRI reconstruction, which leverages inter-slice contextual information to improve reconstruction fidelity. The proposed HSMD consists of a Shallow Feature Extraction Module (SFEM) and five cascaded Multi-Directional Spatial Attention (MDSA) modules. The SFEM is responsible for extracting local detailed features and coarse-scale structural context from undersampled MRI inputs. The MDSA modules extract and fuse multi-directional spatial information along the depth, height, and width dimensions to enhance the representation of 3D structural features. Furthermore, a multi-directional Hilbert selective state-space scanning strategy is introduced into MDSA to capture long-range spatial dependencies within 3D volumetric data, thereby improving structural representation while preserving spatial locality. Experimental results on the BraTS and UCSF-PDGM datasets under diverse acceleration factors validate that the proposed HSMD achieves superior performance over state-of-the-art methods in both quantitative metrics and visual quality. The HSMD exhibits excellent capability in 3D undersampled MRI reconstruction, holding promising prospects for efficient and reliable clinical MRI applications.

Topics

Journal Article

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