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Deep Guess acceleration for explainable image reconstruction in sparse-view CT.

July 1, 2025pubmed logopapers

Authors

Loli Piccolomini E,Evangelista D,Morotti E

Affiliations (3)

  • Department of Computer Science and Engineering, University of Bologna, Via Mura Anteo Zamboni 7, 40126 Bologna, Italy. Electronic address: [email protected].
  • Department of Computer Science and Engineering, University of Bologna, Via Mura Anteo Zamboni 7, 40126 Bologna, Italy.
  • Department of Political and Social Sciences, University of Bologna, Strada Maggiore 45, 40125 Bologna, Italy.

Abstract

Sparse-view Computed Tomography (CT) is an emerging protocol designed to reduce X-ray dose radiation in medical imaging. Reconstructions based on the traditional Filtered Back Projection algorithm suffer from severe artifacts due to sparse data. In contrast, Model-Based Iterative Reconstruction (MBIR) algorithms, though better at mitigating noise through regularization, are too computationally costly for clinical use. This paper introduces a novel technique, denoted as the Deep Guess acceleration scheme, using a trained neural network both to quicken the regularized MBIR and to enhance the reconstruction accuracy. We integrate state-of-the-art deep learning tools to initialize a clever starting guess for a proximal algorithm solving a non-convex model and thus computing a (mathematically) interpretable solution image in a few iterations. Experimental results on real and synthetic CT images demonstrate the Deep Guess effectiveness in (very) sparse tomographic protocols, where it overcomes its mere variational counterpart and many data-driven approaches at the state of the art. We also consider a ground truth-free implementation and test the robustness of the proposed framework to noise.

Topics

Tomography, X-Ray ComputedDeep LearningImage Processing, Computer-AssistedRadiographic Image Interpretation, Computer-AssistedJournal Article

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