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Artificial intelligence-driven soft tissue prediction in virtual surgical planning for orthognathic surgery: a scoping review.

September 14, 2026pubmed logopapers

Authors

Frank D,Albarki Z,Naqeeb M,Kumar R

Affiliations (4)

  • Private Practice, Hobart, Tasmania, Australia. Electronic address: [email protected].
  • Private Practice, Melbourne, Victoria, Australia.
  • Department of Rural Clinical Sciences, La Trobe Rural Health School, Bendigo, Victoria, Australia.
  • Department of Oral and Maxillofacial Surgery, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Abstract

The objective of this study was to map the current evidence on artificial intelligence (AI)-based facial soft tissue prediction in virtual surgical planning (VSP) workflows for orthognathic surgery. A scoping review was conducted using PubMed/MEDLINE, Embase, Scopus, Web of Science and IEEE Xplore databases, in accordance with the Joanna Briggs Institute (JBI) methodology and reported following the PRISMA Extension for Scoping Reviews (PRISMA-ScR). Data on study characteristics, AI methodologies, imaging inputs, accuracy metrics, validation strategies, and levels of integration into VSP were extracted. Six studies met the eligibility criteria. All used deep learning-based models, predominantly using point cloud or surface mesh representations derived from computed tomography (CT), cone-beam computed tomography (CBCT), and/or three-dimensional (3D) surface scans. The reported geometric prediction accuracy was frequently within clinically accepted thresholds (≤ 2-3 mm), although reduced accuracy was consistently observed in dynamic regions. None of the studies adequately evaluated patient-reported outcomes, clinician usability, or full workflow integration with VSP. AI-based soft tissue prediction in VSP workflows demonstrates promising results but remains in an early translational phase. Further research is required to establish its generalisability, workflow integration, and clinical impact.

Topics

Journal ArticleReview

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