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Memory-efficient image reconstruction using diffusion models for accelerated 3D non-Cartesian UTE imaging.

August 19, 2026pubmed logopapers

Authors

Petersen J,Sommer S,Küstner T

Affiliations (5)

  • Medical Image and Data Analysis (MIDAS.lab), Department of Diagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany. [email protected].
  • Research and Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany. [email protected].
  • Swiss Center for Musculoskeletal Imaging (SCMI), Balgrist Campus, Zurich, Switzerland.
  • Swiss Innovation Hub, Siemens Healthineers International AG, Zurich, Switzerland.
  • Medical Image and Data Analysis (MIDAS.lab), Department of Diagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany.

Abstract

Accelerated 3D non-Cartesian MRI presents unique challenges in balancing high-resolution reconstruction with computational and memory constraints. In this work, a novel, memory-efficient image reconstruction framework using score-based diffusion models tailored for highly undersampled 3D radial UTE acquisitions is proposed. The method leverages a volumetric extension of the NCSN++ architecture with efficient NUFFT operations and integrates a conjugate gradient-based data consistency mechanism within a predictor-corrector sampling scheme. This approach enables robust and high-fidelity reconstructions from as few as 4000 spokes-representing up to 50 × undersampling relative to Nyquist. Generalizable performance across knee, ankle, and out-of-distribution shoulder datasets is demonstrated and superior image quality compared to compressed sensing and conventional iterative methods, especially at high acceleration factors is shown. The proposed framework marks a significant step toward practical deployment of diffusion models in non-Cartesian MRI reconstruction.

Topics

Journal Article

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