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Dual branch diffusion-Mamba hybrid network for multi-scale MRI modality translation.

October 24, 2026pubmed logopapers

Authors

Lu C,He Q,Li L,He H,Xiang C,Wei S,Wang H,Wang Z,Wang Q,Yang W

Affiliations (6)

  • Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, China.
  • University of Chinese Academy of Sciences, Beijing, China.
  • Department of Radiology, Peking University Third Hospital, Beijing, China.
  • College of Automation and Electrical Engineering, Shandong University of Aeronautics, Binzhou, China.
  • Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, China. [email protected].
  • University of Chinese Academy of Sciences, Beijing, China. [email protected].

Abstract

Objective MRI modality translation aims to synthesize missing modalities from acquired scans. However, existing methods often struggle to preserve local details while maintaining global structural consistency. We propose a dual-branch diffusion-Mamba hybrid network (DBDM-Net) to address this challenge. Materials and methods DBDM-Net consists of a diffusion-based local branch for fine-detail reconstruction and a Mamba-based global branch for structural coherence preservation. A local feature extraction encoder enhances local representations, while a modulation block and a cross-scale fusion block enable modality-specific adaptation and multi-scale feature integration. Results DBDM-Net achieves competitive PSNR, SSIM, and perceptual quality compared with representative baseline methods. Discussion The proposed dual-branch framework effectively combines local detail reconstruction with global structural modeling, supporting its utility for MRI modality translation.

Topics

Journal Article

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