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Model Confidence and Reader Expertise Shape LLM Use in Chest Imaging

AuntMinnieIndustry

Radiologists' expertise and LLM model confidence independently affect diagnostic collaboration when using AI for chest imaging.

Key Details

  • 1Study involved 10 readers evaluating 100 chest imaging cases (x-ray, CT, MRI, PET) with LLM support.
  • 2High-accuracy LLM (text input, GPT-5) achieved 76% accuracy; low-accuracy LLM (vision input, GPT-4o) achieved 27% accuracy.
  • 3Model confidence (OR 3.82, p=0.003) and reader expertise (OR 2.06, p<0.001) significantly improved reader-LLM interaction.
  • 4High-quality LLM rationales lowered rejection of correct advice (OR 0.79, p=0.005) but raised acceptance of incorrect advice (OR 1.71, p<0.001).
  • 5Expertise reduced susceptibility to incorrect suggestions (OR 0.54, p<0.001).

Why It Matters

Understanding the interplay between model confidence, rationale quality, and user expertise is crucial for optimizing LLM-assisted diagnostics in radiology. The study highlights the double-edged nature of LLM 'explanations' and the continuing importance of radiologist training to mitigate overreliance on AI.

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